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Aqemia SAS logo

SRE - Platform Engineer

Job Overview

Location

Paris

Job Type

Full-time

Category

Software Engineering

Date Posted

December 19, 2025

Full Job Description

📋 Description

  • • Own the beating heart of Aqemia’s drug-discovery engine. You will architect, build, and harden the cloud-native platform that lets 65 chemists, physicists, and ML researchers push 10⁾ molecules per day through quantum-inspired simulations and generative-AI pipelines.
  • • Guarantee 99.9 % uptime for mission-critical services that predict binding affinity, enumerate novel scaffolds, and orchestrate terabyte-scale molecular dynamics—because every minute of downtime delays a potential therapy for cancer, inflammation, or CNS disorders.
  • • Codify everything. Write Terraform/Terragrunt modules that spin up multi-AZ Kubernetes clusters on AWS, wire IAM least-privilege policies, and provision GPU node groups that scale from 0 to 500 A100s in under five minutes—then open-source the modules internally so every squad can reproduce your stack with one CLI command.
  • • Design bullet-proof CI/CD. Extend GitHub Actions workflows with matrix builds that test 40 micro-services in parallel, integrate ArgoCD for GitOps promotion across dev, staging, and production, and cut deployment time from 25 min to <5 min while adding canary and blue-green strategies that protect live experiments.
  • • Make scientists’ lives friction-free. Build self-service portals where chemists click once to launch containerized Jupyter notebooks pre-loaded with 2 TB of proprietary assay data, or spin up transient Ray clusters for hyper-parameter sweeps—no YAML wrestling required.
  • • Define, measure, and evangelize SLOs. Instrument FastAPI services with OpenTelemetry, pipe traces to Grafana Tempo, and create SLIs that track “molecules evaluated per hour” and “model convergence time.” Run weekly error-budget reviews with ML teams to balance velocity and reliability.
  • • Automate incident response. Create PagerDuty playbooks, Terraform-managed runbooks, and Slack-driven ChatOps commands that roll back bad releases, restart failed Airflow DAGs, or drain misbehaving GPU nodes—cutting MTTR from 40 min to <10 min.
  • • Optimize for cost and carbon. Implement Karpenter-based auto-scaling policies that save 35 % on EC2 spend, schedule non-urgent batch jobs on Spot GPUs, and publish monthly dashboards that show CO₂ saved per molecule discovered.
  • • Secure the entire supply chain. Integrate Trivy scanning in CI, sign container images with Cosign, enforce OPA policies in Kubernetes admission controllers, and run chaos-engineering drills that prove secrets stay sealed even when etcd misbehaves.
  • • Influence the technical roadmap. Sit at the table with the CTO, Head of ML, and Head of Chemistry to translate “we need to screen 1 M molecules in 24 h” into concrete infra epics, capacity plans, and quarterly OKRs.
  • • Coach and uplift peers. Run internal workshops on Terraform testing, mentor junior engineers through pair-programming, and write decision records (ADRs) that turn tribal knowledge into living documentation.
  • • Celebrate real-world impact. When your platform ships a feature that shaves two weeks off lead-optimization timelines, join the all-hands to hear chemists explain how those two weeks may translate into patients getting life-saving drugs sooner.

Skills & Technologies

Python
FastAPI
AWS
Docker
Kubernetes
DevOps
Senior
Remote

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Aqemia SAS
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About Aqemia SAS

Aqemia is a Paris-based drug-discovery company founded in 2019 that combines deep physics algorithms with generative AI to predict the potency and safety of drug candidates. Its platform screens billions of small molecules in silico, prioritizing candidates for synthesis and experimental validation. The company partners with pharmaceutical firms and biotechs to accelerate hit-to-lead and lead-optimization programs across oncology, immunology, and neurology. Aqemia’s pipeline includes internal assets and collaboration projects, aiming to shorten development timelines and reduce early-stage R&D costs while maintaining high success rates in identifying novel therapeutic candidates.

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