Job Overview
Location
Boston Office
Job Type
Full-time
Category
Software Engineering
Date Posted
May 22, 2026
Full Job Description
đź“‹ Description
- • Lead the design and evolution of scalable, highly available AWS cloud infrastructure to support Iambic’s drug discovery platform, Computational Science applications, and Machine Learning models.
- • Support and contribute to the Cloud Ops roadmap by aligning infrastructure initiatives with organizational business priorities and technical goals.
- • Provide technical leadership across platform and infrastructure teams, driving architecture decisions and influencing Cloud Ops best practices organization-wide.
- • Build and operate production systems with a strong focus on reliability, performance, and cost efficiency in a life sciences environment.
- • Design and manage cloud networking including VPCs, Transit Gateways, Customer Gateways, VPNs, routing, DNS, load balancing, security groups, and NACLs.
- • Implement Infrastructure as Code using Terraform and Terragrunt to automate provisioning, configuration, and operational workflows.
- • Automate CI/CD pipelines to improve deployment velocity, stability, and observability across ML and software systems.
- • Troubleshoot complex distributed system issues including networking bottlenecks, deployment failures, and Kubernetes service disruptions on AWS EKS.
- • Apply security best practices and actively support ISO 27001 compliance frameworks for cloud operations and data handling.
- • Manage and optimize AWS IAM policies, roles, and permissions to ensure least-privilege access across teams and systems.
- • Deploy and maintain Kubernetes clusters on AWS EKS, including managing zero-downtime upgrades, debugging controllers, and monitoring cluster health.
- • Leverage Cloudflare networking solutions for secure connectivity, DNS management, and DDoS protection across global access points.
- • Collaborate with ML engineers to address challenges in model training, inference, and deployment scalability within cloud environments.
- • Mentor engineers in cloud services, infrastructure automation, and operational excellence, fostering a culture of shared ownership and continuous improvement.
- • Work closely with IT, Computational Scientists, Software Developers, and ML teams to ensure seamless integration of cloud infrastructure with scientific and software workflows.
- • Maintain high operational maturity through observability tooling, incident response protocols, and proactive system monitoring.
- • Fully support remote work but prefer candidates located in Boston, with workspace support available at the Boston office.
🎯 Requirements
- • Minimum of 12 years of related experience with a bachelor’s degree; or 10 years and a master’s degree; or equivalent experience.
- • Strong Infrastructure as Code skills using Terraform and Terragrunt.
- • Strong understanding of AWS services including IAM, EKS, VPC, Transit Gateways, Customer Gateways, security groups, NACLs, and flow logs.
- • Strong understanding of CI/CD pipelines and automation for production systems.
- • Strong understanding of computer networks: TCP/IP protocols, IP block allocation, routing, and VPN protocols.
- • Cloudflare networking experience and familiarity with ML deployment challenges including model training and inference.
🏖️ Benefits
- • Industry-leading competitive pay
- • Company-paid healthcare
- • Flexible spending accounts
- • Voluntary life insurance
- • 401K matching
- • Uncapped vacation
Skills & Technologies
About Iambic Therapeutics, Inc.
Iambic Therapeutics is a biotechnology company leveraging a cutting-edge, AI-driven platform to revolutionize drug discovery and develop superior medicines. Utilizing physics-based AI algorithms and high-throughput experimental processes, Iambic addresses challenging design problems to generate optimized drug candidates and explore novel mechanisms of action. Their platform-driven pipeline focuses on first-in-class and best-in-class programs, including a HER2 program already in Phase 1 clinical studies, aimed at unlocking the potential of known targets and transforming undruggable targets into breakthrough treatments for patients with unmet medical needs. This innovative approach enables them to deliver differentiated clinical candidates at an accelerated pace, supported by over $100 million raised in an oversubscribed financing round to advance their portfolio.
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