Amgen Inc. logo

Principal Engineer - Global Reliability Network Lead (Remote)

Job Overview

Location

2 Locations

Job Type

Full-time

Category

Engineering Manager

Date Posted

June 3, 2026

Full Job Description

📋 Description

  • Lead Amgen’s Global Reliability Network as part of Engineering Operations Services (EOS), managing a network of site reliability engineers, maintenance leaders, system owners, and technical SMEs.
  • Develop and execute the Reliability Network strategy, including goals, milestones, and maturity plans to improve asset reliability, equipment availability, maintenance effectiveness, and operational capacity.
  • Share reliability KPIs, bad actor trends, equipment improvements, lessons learned, and reusable solutions across Amgen’s manufacturing sites.
  • Represent reliability priorities and recommendations in senior engineering governance forums.
  • Use CMMS data, Asset Performance Monitoring, PlantPulse, PdM findings, and site input to identify recurring failures, high-risk assets, downtime drivers, and critical equipment issues.
  • Convert reliability insights into corrective actions, equipment improvements, PM/PdM optimization, spare parts strategies, and capital investment recommendations.
  • Track improvement actions, verify benefits, and scale successful practices across global manufacturing sites.
  • Define and maintain a standardized risk-based asset criticality approach across all sites to prioritize maintenance strategies, work execution, spare parts allocation, lifecycle planning, and performance monitoring.
  • Standardize maintenance strategies based on asset criticality, failure modes, operating context, and historical performance data.
  • Support RCM, FMEA/FMECA, PM optimization, predictive maintenance, and condition-based maintenance methodologies.
  • Serve as the business owner for the CMMS Asset Performance Monitoring module and PlantPulse tools, ensuring they address reliability pain points and generate actionable equipment insights.
  • Partner with SAP EAM, Technology/IS, site engineering teams, and SMEs to support deployment, training, adoption, and data quality for reliability systems.
  • Define business requirements for asset health, criticality, failure modes, risk ranking, performance monitoring, and continuous improvement initiatives.
  • Partner with OPEX teams to identify reliability improvements that unlock capacity and reduce downtime.
  • Translate recurring failures and reliability constraints into measurable business impact, including cost, capacity, and operational efficiency.
  • Support lifecycle risk visibility for critical assets, including deterioration, obsolescence, maintenance cost, reliability concerns, and end-of-life planning.
  • Integrate reliability principles into capital projects from conceptual design through turnover.
  • Ensure fluent English proficiency in written and verbal communication for global collaboration.
  • Be available to commute to the nearest Amgen operation site as business needs arise for meetings, training, operational support, or other critical activities.

Skills & Technologies

Senior
Onsite
Degree Required

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Amgen Inc.
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About Amgen Inc.

Amgen Inc. is a global biotechnology company headquartered in Thousand Oaks, California. Founded in 1980, it discovers, develops, manufactures, and delivers human therapeutics targeting cancer, kidney disease, rheumatoid arthritis, bone disease, and other serious illnesses. Using advanced recombinant DNA and molecular biology techniques, Amgen produces biologic medicines such as Neulasta, Enbrel, and Prolia. The company operates R&D, manufacturing, and distribution facilities worldwide, investing heavily in genomic research to identify novel drug targets. Amgen also partners with academic institutions and smaller biotechs to expand its pipeline, aiming to transform breakthrough science into therapies that significantly improve patients’ lives.

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