Experienced Clinical Trial Manager

Syneos Health, Inc.

Job Overview

Location

DEU-Remote

Job Type

Full-time

Full Job Description

📋 Description

• Responsible for end-to-end oversight of clinical trial activities for a single client partnership in Germany, ensuring compliance with protocol, GCP, and regulatory requirements.
• Manage site management, clinical monitoring, and central monitoring deliverables with a focus on patient safety, data integrity, and trial conduct.
• Oversee all site interactions from activation through closeout, including patient recruitment, investigator payments, and site performance.
• Review study scope of work, budget, and protocol content to ensure clinical team members understand contractual obligations and parameters.
• Identify critical data and process risks using operational data, metrics, and reports, and implement risk mitigations through strategic problem-solving.
• Escalate risks to timeline, quality, or budget, and flag activities outside contracted scope to the project manager.
• Serve as the primary escalation point for communication with investigator site staff, including phone or in-person interactions with principal investigators.
• Participate in and present at key meetings such as Kick-Off Meetings and coordinate handoffs with Study Start Up, Patient Recruitment, and Data Management teams.
• Develop and maintain clinical study tools and templates, including the Clinical Monitoring Plan, and ensure CTMS, dashboards, and other systems are properly configured and validated.
• Oversee user acceptance testing (UAT) for clinical systems and ensure audit trails and access reviews are completed as required.
• Deliver initial and ongoing training to study teams on protocol specifics, CRF completion, dashboards, SOPs, clinical plans, and data timelines.
• Manage resourcing allocations for CRAs and Central Monitors, assign sites, and monitor team conduct for quality and compliance.
• Review site and central monitoring documentation (visit reports, letters, central monitoring reports) to ensure accuracy, completeness, and alignment with sponsor and company standards.
• Monitor clinical trial systems (CTMS, EDC, eDiary, ePRO, TMF, IVRS/IWRS, Central Monitoring dashboards) to track site activities, patient visits, and operational execution against plan.
• Contribute to the development of risk-based monitoring strategies and ensure team compliance with the Clinical Monitoring Plan and risk mitigation plans.
• Interact directly with clients and cross-functional departments to provide status updates on clinical deliverables, risks, and solutions for protocol execution challenges.
• Support inspection readiness for clinical trial management activities and demonstrate understanding of roles across Data Management, Medical Monitoring, Pharmacovigilance, and Quality Assurance.
• Assess CRA and Central Monitor compliance with study processes, training, and monitoring plans; develop and support corrective action plans as needed.
• Provide performance feedback to line managers on team members’ strengths and development areas, particularly on complex or large-scale trials.
• Moderate travel (approximately 20%) may be required for site visits, meetings, or training sessions.

🎯 Requirements

• Bachelor’s degree or RN in a related field or equivalent combination of education, training, and experience
• Demonstrated expertise in site management and clinical or central monitoring
• Fluency in both German and English
• Strong background as a Clinical Trial Manager
• Knowledge of Good Clinical Practice/ICH Guidelines and applicable regulatory requirements
• Demonstrated ability to lead teams and align them toward project milestones

🏖️ Benefits

• Career development and progression opportunities
• Supportive and engaged line management
• Technical and therapeutic area training
• Peer recognition and total rewards program
• Inclusive culture focused on authenticity and purpose
• Opportunities to work on global clinical trials impacting patient progress

Skills & Technologies

GCP

Remote

Degree Required

Ready to Apply?

Apply Externally

You will be redirected to an external site to apply.

AI Job Fit Analysis

Pro

See exactly how your profile matches this role — strengths, skill gaps, and what to do about them.

Syneos Health, Inc.

Visit Website

About Syneos Health, Inc.

Syneos Health is a global biopharmaceutical services organization providing clinical and commercial solutions. It integrates clinical development, outsourced commercialization, consulting, and communications services to accelerate the delivery of therapies to market. The company supports pharmaceutical, biotechnology, and medical device clients across all phases of product development and commercialization, operating in North America, Europe, and Asia-Pacific.

View Company Profile

Get more remote jobs like this

Subscribe to the weekly newsletter for similar remote roles and curated hiring updates.

Weekly remote jobs and featured talent.

No spam. Only curated remote roles and product updates. You can unsubscribe anytime.