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Principal Software Engineer I

Job Overview

Location

United States Remote

Job Type

Full-time

Category

Software Engineering

Date Posted

June 23, 2026

Full Job Description

đź“‹ Description

  • • Design and develop software application deployments for global clinical research technology platforms.
  • • Implement full CI/CD pipelines and automate deployment workflows to ensure consistent, reliable software releases.
  • • Create and execute automated testing routines to guarantee stable, error-free deployments across production environments.
  • • Support DevOps initiatives by eliminating manual release and build processes through automation.
  • • Develop and manage infrastructure automation and cloud environments using AWS and Azure.
  • • Train IT and development teams on infrastructure automation best practices and standardized operational procedures.
  • • Monitor and maintain software security, performance metrics, and service level agreements (SLAs) for critical clinical systems.
  • • Provide Tier III support for production applications, resolving complex technical issues and ensuring optimal functionality.
  • • Lead technical design decisions for software systems that support scalable, secure, and compliant clinical trial operations.
  • • Collaborate closely with engineering, IT, and operations teams to accelerate evidence generation and decision-making in global clinical trials.
  • • Conduct requirement analysis and write unit test cases to ensure code quality and system reliability.
  • • Drive technical excellence by mentoring engineers, reviewing code, and fostering a culture of continuous improvement.
  • • Manage and develop high-performing software engineering teams in a collaborative, cross-functional environment.
  • • Work within Agile development frameworks to deliver iterative improvements and maintain sprint cadence.
  • • Maintain comprehensive documentation for systems, processes, and automation scripts to ensure knowledge retention and team alignment.
  • • Ensure all software systems adhere to regulatory compliance standards relevant to clinical research and healthcare data.

🎯 Requirements

  • • Bachelor’s degree in Computer Science, Software Engineering, or related field
  • • Minimum of 8+ years of professional software development experience
  • • Proven, hands-on experience with .NET, C#, and senior-level expertise in ASP.NET MVC
  • • Strong background in SQL, PL/SQL, and Postgres with a backend database focus
  • • Experience leading and managing Software Engineering teams, including mentoring and overseeing project delivery
  • • Demonstrated ability to work in Agile development environments

🏖️ Benefits

  • • Competitive compensation
  • • Medical, dental, and vision insurance beginning Day 1 of employment
  • • Flexible work schedules
  • • Attractive PTO plan
  • • Engaging employee programs
  • • Remote working

Skills & Technologies

ASP.NET
PostgreSQL
AWS
Azure
Jenkins
Senior
Remote
Degree Required

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About Clario

Clario is a global healthcare technology and services company that provides endpoint data solutions for clinical trials. It delivers imaging, cardiac safety, respiratory, eCOA, and precision motion technologies, supported by scientific and regulatory expertise, to help biopharmaceutical sponsors generate high-quality evidence and accelerate drug development.

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