Job Overview
Location
San Francisco
Job Type
Full-time
Category
Product Management
Date Posted
March 18, 2026
Full Job Description
đź“‹ Description
- • As a Product Manager focused on biosecurity risk within OpenAI’s Safety Systems team, you will play a critical role in ensuring that frontier AI models are developed and deployed responsibly, with a specific emphasis on mitigating biological safety risks. Your work will directly contribute to OpenAI’s mission of building safe Artificial General Intelligence (AGI) by aligning technical innovation with rigorous safety standards, policy insights, and ethical considerations.
- • You will partner closely with AI researchers, software engineers, data scientists, policy experts, and cross-functional stakeholders to embed safety throughout the model lifecycle—from training and evaluation to deployment and monitoring—ensuring that biosecurity considerations are systematically integrated into product development.
- • You will develop comprehensive frameworks for identifying, assessing, and mitigating deployment-related biosecurity risks, leveraging data analysis, adversarial testing, expert consultation, and scenario planning to anticipate and reduce potential misuse of AI in biological contexts.
- • You will define strategic priorities and build product roadmaps that advance deployment safety, improve system reliability, and address emerging capabilities in AI that could pose biosecurity threats, balancing innovation with precaution.
- • You will create scalable tools, methodologies, and processes for evaluating safety performance, refining safeguards, and continuously improving OpenAI’s safety systems based on real-world feedback and research advancements.
- • You will establish repeatable processes to translate cutting-edge AI safety research—particularly in biosecurity and dual-use risk—into actionable product features, model updates, and deployment protocols.
- • You will design and refine clear, actionable metrics that measure safety performance at scale, enabling data-driven decisions about model behavior, user impact, and risk mitigation effectiveness across global deployments.
- • You will foster collaboration across disciplines, helping to build consensus in ambiguous, high-stakes environments by challenging assumptions, facilitating structured dialogue, and aligning diverse teams around shared safety objectives.
- • You will contribute to uplifting the broader AI safety ecosystem by sharing insights, developing best practices, and enabling others to strengthen their own defenses against AI-enabled biological risks.
🎯 Requirements
- • 6+ years of product management or related industry experience, with demonstrated expertise in AI safety, trust & safety, integrity, or closely related domains.
- • Academic or professional background in biology, life sciences, or a related field, enabling informed engagement with biosecurity concepts and risks.
- • Proven ability to drive consensus and take initiative in ambiguous, complex problem spaces through structured analysis and collaborative decision-making.
- • Strong skills in cross-functional collaboration and communicating technical and safety-related concepts clearly to both technical and non-technical audiences.
- • Deep curiosity and interest in interdisciplinary areas such as human-computer interaction, psychology, philosophy, or ethics, particularly as they relate to AI safety and societal impact.
- • Experience developing frameworks, roadmaps, or metrics for safety-critical systems, preferably in high-stakes or regulated environments.
🏖️ Benefits
- • Competitive compensation package including base salary, equity, and performance-based bonuses aligned with OpenAI’s mission-driven culture.
- • Comprehensive health, dental, and vision insurance plans, plus mental health resources and wellness programs to support holistic well-being.
- • Generous relocation assistance for candidates moving to San Francisco, including temporary housing and moving expense support.
- • Access to cutting-edge AI research, internal tech talks, and learning opportunities with leading experts in AI safety, policy, and engineering.
- • Flexible work arrangements and a culture that values psychological safety, inclusivity, and intellectual curiosity.
- • Opportunity to work on some of the most impactful and technically challenging safety problems in AI, with direct influence on the responsible development of frontier models.
Skills & Technologies
Product Management
Onsite
About OpenAI, Inc.
OpenAI is a San Francisco-based artificial intelligence research and deployment company founded in 2015. It develops large-scale AI models such as GPT, DALL-E, and Codex, providing cloud APIs and consumer applications like ChatGPT. Originally established as a non-profit, it later created a capped-profit subsidiary to attract capital while maintaining its mission to ensure artificial general intelligence benefits all of humanity.
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