Job Overview
Location
Menlo Park, CA
Job Type
Full-time
Category
DevOps & SysAdmin
Date Posted
April 23, 2026
Full Job Description
đź“‹ Description
- • As a Staff Site Reliability Engineer (SRE) / DevOps Engineer at GRAIL, you will lead the reliability, scalability, and security of the company’s cloud-native platform, directly supporting systems that power large-scale data processing and cutting-edge cancer detection technologies.
- • Your day-to-day responsibilities include defining and driving infrastructure standards across engineering teams, representing reliability and performance in architectural decisions, and building scalable systems that extend beyond your direct ownership through hands-on engineering and cross-functional influence.
- • You will join a multidisciplinary team of scientists, engineers, and physicians at GRAIL, a healthcare company pioneering early cancer detection using next-generation sequencing, population-scale clinical studies, and advanced data science, with headquarters in Menlo Park, CA (transitioning to Sunnyvale in Fall 2026).
- • In this role, you will deepen your expertise in cloud infrastructure, platform engineering, and system reliability while mentoring peers and shaping technical strategy that impacts life-saving cancer detection innovations.
🎯 Requirements
- • Expertise in cloud-native infrastructure, including experience with Kubernetes, containerization, and cloud platforms (AWS, GCP, or Azure)
- • Proven ability to design and implement scalable, reliable, and secure systems for large-scale data processing workloads
- • Strong background in infrastructure-as-code (IaC) using tools like Terraform or CloudFormation
- • Experience with monitoring, logging, and observability stacks (e.g., Prometheus, Grafana, ELK, Datadog)
- • Demonstrated leadership in driving technical standards and influencing architecture decisions across teams
- • Proficiency in scripting and automation using languages such as Python, Bash, or Go
🏖️ Benefits
- • Opportunity to work on mission-critical systems that directly contribute to early cancer detection and improved patient outcomes
- • Hybrid work model with onsite expectations transitioning to a new headquarters in Sunnyvale, CA beginning Fall 2026
- • Access to cutting-edge technology and collaboration with multidisciplinary experts in genomics, data science, and clinical research
- • Professional growth through mentorship, cross-functional leadership, and influence on platform strategy at a rapidly scaling healthcare innovator
Skills & Technologies
About GRAIL, Inc.
GRAIL develops multi-cancer early-detection blood tests using high-intensity sequencing, population-scale clinical trials, and machine learning. Its Galleri test screens for over 50 cancers from a single blood draw, aiming to shift diagnosis from late-stage symptoms to early, treatable stages. The company conducts large prospective studies, partners with health systems, and pursues FDA approval to integrate screening into routine care. Founded in 2016 as a spin-out from Illumina, GRAIL operates laboratories in the United States and the United Kingdom and focuses on evidence generation, regulatory science, and equitable test access.
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