Job Overview
Location
Remote - TN
Job Type
Full-time
Category
Data Science
Date Posted
May 13, 2026
Full Job Description
đź“‹ Description
- • The Senior Computational Research Scientist leads, performs, and develops computational research projects under minimal supervision, driving discovery of novel small molecule modulators for pediatric disease targets.
- • Day-to-day responsibilities include leading computationally focused research projects, developing new computational methods, identifying and interpreting complex data, directing data collection, presenting findings internally and externally, drafting manuscripts, and training and overseeing others in computational techniques.
- • The role is situated within the Department of Chemical Biology and Therapeutics at ALSAC/St. Jude Children's Research Hospital, a mission-driven institution dedicated to advancing cures and prevention for pediatric catastrophic diseases through research and treatment.
- • The individual will deepen expertise in computer-aided drug design, molecular dynamics, docking, pharmacophore modeling, QSAR, and chemical informatics while gaining experience in collaborative translational science environments and high-performance computing resources.
🎯 Requirements
- • Bachelor’s degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field; Master’s degree or PhD preferred.
- • Minimum of 7+ years of relevant experience with Bachelor’s degree (or equivalent via Master’s +5 years or PhD +2 years).
- • Strong background in computational chemistry including molecular dynamics simulations, molecular docking, pharmacophore modeling, QSAR modeling, and chemical informatics.
- • Proficiency in scientific computing languages such as R and Python, and experience with open-source tools like Knime, RDKit, and ChemProp.
- • Experience using high performance computing resources and developing/maintaining chemical and biological databases.
- • Proven track record of research output, including 1-2 first-author papers with impact factor >10 or equivalent contributions.
🏖️ Benefits
- • Access to St. Jude’s exceptional benefits package, including health, retirement, and wellness programs.
- • Opportunity to work remotely (based in TN) while contributing to impactful pediatric disease research.
- • Collaborative, mission-driven environment working alongside biologists, chemists, pharmacologists, and shared translational science resources.
- • Support for professional development through training others and leading independent research initiatives.
- • Employer committed to equal opportunity and inclusive workplace practices.
Skills & Technologies
About ALSAC/St. Jude Children's Research Hospital
ALSAC, the fundraising and awareness organization for St. Jude Children's Research Hospital, supports the Memphis-based pediatric treatment and research facility founded in 1962. St. Jude provides care for children with cancer and other life-threatening diseases regardless of a family's ability to pay, while conducting research to advance cures and prevention. ALSAC raises the majority of funds needed to operate St. Jude through donations, events, and partnerships, ensuring continued expansion of research programs and global outreach initiatives.
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